New ink formulated to print living human tissue
Scientists are one step closer to being able to print tissue replacements for diseased or damaged body parts using inkjet printers, thanks to the development of a specialised ink formulation.
Researchers have been aware for some time of the potential for using commercially available inkjet printer heads to print living human cells into 3D structures, but design of the actual ink capable of carrying cells through the printer has been a challenge.
The ARC Centre of Excellence for Electromaterials Science at UOW has led a team of scientists including Cameron Ferris, Dr Kerry Gilmore, Dr Stephen Beirne, Dr Donald McCallum, Prof Gordon Wallace and A/Prof Marc in het Panhuis to develop a new bio-ink that improves the viability of living cells and allows better control of cell positioning through the printing process.
“To date, none of the available inks have been optimised in terms of both printability and cell suspending ability,” said ACES Associate Researcher Cameron Ferris, pictured at top.
“Our new bio-ink is printable and cell-friendly, preventing cell settling and allowing controlled deposition of cells.”
The 2D structures being printed with the bio-ink enables exquisite control over cell distribution and this already presents exciting opportunities to improve drug screening and toxicology testing processes. Building on this, 3D bio-printing, with which patient-specific tissue replacements could be fabricated, is within the grasp of researchers.
“The development of chemistries that enable fabrication protocols not only takes us closer to practical devices but gives us experimental protocols that allows previously unexplored areas of fundamental science to be explored,” said ACES Director Prof Gordon Wallace.